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测定了80例糖尿病、高血压病及各类肾、泌尿系疾病患者尿中N-乙酰-β-D氨基葡萄糖苷酶(NAG),γ-谷氨酰转移酶(γ-GT),乳酸脱氢酶(LDH),碱性磷酸酶(ALP)的活性及尿微量白蛋白(Alb)的含量。同时测定了102例健康人尿样。统计结果表明:各类肾病患者的四种尿酶活性及微量Alb含量均显著高于健康对照组(P<0.05)。提示联合测定尿酶谱及微量Alb,不但可以提高患者潜在肾损伤的阳性检出率,且对于了解各类肾损伤患者的肾损伤程度,病情发展,疗效观察,预后判断都有较大的临床意义。
The urinary N-acetyl-β-D-glucosaminidase (NAG), γ-glutamyl transferase (γ-GT) and lactate were measured in 80 patients with diabetes, hypertension and various renal and urinary diseases. (LDH), alkaline phosphatase (ALP) activity and urine microalbumin (Alb) content. At the same time, 102 cases of healthy people urine samples were measured. The statistical results show that: all kinds of kidney disease patients with four kinds of urinary enzyme activity and trace Alb content were significantly higher than the healthy control group (P <0.05). Prompt combined determination of urinary enzymes and trace Alb, not only can improve the detection rate of potential renal injury in patients with kidney injury, and for understanding the extent of renal injury, disease progression, efficacy, prognosis have a larger clinical significance.