辐射旁效应是指未直接受照射的细胞表现出与受照射细胞类似的生物学反应,包括如细胞死亡、细胞间活性氧增加、细胞增生、凋亡、染色体断裂和突变、基因改变、基因不稳定等[1]。本文将对辐射引起的旁效应及其相关进展做一综述。1辐射旁效应的客观存在旁效应最早由Nagasawa和Litt Bystander effect refers to the fact that cells that are not directly irradiated exhibit similar biological responses to irradiated cells and include, for example, cell death, increased intracellular reactive oxygen species, cell proliferation, apoptosis, chromosomal breaks and mutations, genetic alterations, Stability [1]. This article will review the side effects caused by radiation and its related progress. 1 The side-by-side effect of radiation side effects was first observed by Nagasawa and Litt