依达拉奉注射液联合甘油果糖治疗高血压性脑出血的临床疗效

来源 :现代生物医学进展 | 被引量 : 0次 | 上传用户:dengliguo1971
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目的:探讨依达拉奉联合甘油果糖治疗高血压性脑出血的临床疗效。方法:根据患者的意愿将120例高血压性脑出血患者分成观察组(56例)和对照组(64例)。对照组患者给予依达拉奉联合甘露醇治疗;观察组患者采用依达拉奉联合甘油果糖治疗15d。观察两组患者治疗后临床疗效、神经功能恢复评分及肾功能损害情况。结果:1观察组患者治疗后总有效率为73.21%(41/56),明显高于对照组患者总有效率35.9%(25/64),差异有统计学意义(P<0.05);2治疗后两组患者的NIHSS评分均低于治疗前,治疗后观察组患者NIHSS评分为(4.29±5.6)明显低于对照组患者评分(7.09±4.9),差异均有统计学意义(P<0.05);3治疗后观察组患者肾功能损害情况评分明显低于对照组患者,差异有统计学意义,(P<0.05)。结论:采用依达拉奉联合甘油果糖治疗高血压性脑出血患者,疗效确切且不良反应少,值得临床推广应用。 Objective: To investigate the clinical efficacy of edaravone combined with glycerol fructose in the treatment of hypertensive intracerebral hemorrhage. Methods: According to the wishes of patients, 120 patients with hypertensive intracerebral hemorrhage were divided into observation group (56 cases) and control group (64 cases). Patients in the control group were given edaravone combined with mannitol. Patients in the observation group were treated with edaravone combined with glycerol fructose for 15 days. The clinical efficacy, nerve function recovery scores and renal dysfunction of the two groups were observed after treatment. Results: 1 The total effective rate of the observation group was 73.21% (41/56) after treatment, which was significantly higher than that of the control group (35.9%, 25/64) (P <0.05) The NIHSS scores of the latter two groups were lower than those before treatment, and the NIHSS score of the observation group was significantly lower than that of the control group (4.29 ± 5.6) after treatment (7.09 ± 4.9) (P <0.05) ; 3 after treatment, the score of renal dysfunction in the observation group was significantly lower than that of the control group, the difference was statistically significant (P <0.05). Conclusion: Edaravone combined with glycerol fructose in patients with hypertensive cerebral hemorrhage, the exact effect and fewer adverse reactions, it is worthy of clinical application.
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