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目的:比较老年人外周动脉压与中心动脉压的差异,探讨二者与冠心病的关系以及可能的机制。方法:收集2010年9月至2012年1月在北京航天总医院行诊断性冠状动脉造影的386例老年的临床资料,分为冠心病组(212例)和非冠心病组(174例)。比较两组患者外周肱动脉压与中心动脉压的差异。结果:肱动脉袖带收缩压(SBP)与肱动脉内压力波测量的SBP相近,两者的升降呈平行改变,具有显著相关性(P<0.01)。两组患者的外周动脉压与中心动脉压比较,差异有统计学意义(P<0.05);其中冠心病组患者的外周动脉压与中心动脉压差异更为显著。两组间各项指标比较,差异均有统计学意义(P<0.05)。结论:外周动脉压与中心动脉压间存在差异;冠心病患者外周动脉压明显低于中心动脉压;中心动脉硬化可能与外周SBP低于中心SBP有关。
Objective: To compare the difference between peripheral arterial pressure and central arterial pressure in the elderly and explore their relationship with coronary heart disease and its possible mechanism. Methods: The clinical data of 386 elderly patients with diagnostic coronary angiography at Beijing Aerospace General Hospital from September 2010 to January 2012 were collected and divided into coronary heart disease (212 cases) and non-coronary heart disease (174 cases). The differences of brachial artery pressure and central arterial pressure between the two groups were compared. Results: The brachial artery systolic pressure (SBP) was similar to that of brachial artery pressure wave measurement. There was a significant correlation between SBP and brachial artery pressure wave (P <0.01). The difference of peripheral arterial pressure and central arterial pressure between the two groups was statistically significant (P <0.05). The difference between peripheral arterial pressure and central arterial pressure was more significant in patients with coronary heart disease. The indicators between the two groups, the differences were statistically significant (P <0.05). Conclusion: There is difference between peripheral arterial pressure and central arterial pressure; peripheral arterial pressure in patients with coronary heart disease is significantly lower than that of central artery; central arteriosclerosis may be related to peripheral SBP lower than central SBP.