每年有许多药物被批准上市,新药上市前几乎从不对妊娠妇女作过试验,以测定该产品对胎儿的影响,参与新药Ⅰ、Ⅱ、Ⅲ临床试验的又多为男性,大部分药品没有标出妊娠妇女如何使用,因而对妊娠妇女临床医生难以判断其对孕妇与胎儿的作用。即使上市后也很少有对妊娠妇女和胎儿作用的报道。迄今,仅了解少数药的危险性,不少妇女服药时并不知道自己怀孕从而使胎暴露于药物下;近来怀孕妇女年龄偏大,有些有长期服药史,这些均对胎儿不利。 Many drugs are approved for listing every year. Pregnant women are almost never tested before the new drug is introduced to determine the impact of the product on the fetus. Most of the new drugs involved in clinical trials of Ⅰ, Ⅱ and Ⅲ are men, most of which are not marked Pregnant women how to use, so clinicians pregnant women difficult to determine their role in pregnant women and the fetus. Even after listing, there are few reports of the effects on pregnant women and fetuses. So far, only a few drugs are known to be dangerous, and many women do not know they are pregnant when they take the medicine so that the fetus is exposed to drugs. Recently pregnant women are older and some have long-term medication history, which are unfavorable to the fetus.