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目的研究持续低频共振条件下大鼠血压、心率、呼吸频率和体温等生理指标变化特点,为生物体器官共振损伤及其反应研究奠定基础。方法 SD大鼠32只,随机分为假振动组、3 Hz频率振动组、6 Hz频率振动组和21 Hz频率振动组1,.5%戊巴比妥钠麻醉后,行股动脉插管,然后将大鼠以仰卧姿固定在振动台上,静置30 min以后,振动组施加振幅(p-p)为5 mm正弦振动,观测振动之前和振动1,3,5,10,30,601,20,1802,40,3003,60 min的血压、心率、呼吸频率、体温等生理指标,假振动组观测相应时间点的上述生理指标。结果持续低频共振会引起大鼠的血压、心率、呼吸频率在振动1 min时迅速升高,1～3 min达到最大值,之后逐渐下降3,0 min后低于正常值,而在振动初期共振不会对大鼠体温造成影响,体温在振动10 min之后才缓慢降低。在振动初期6 Hz频率共振对大鼠血压、心率、呼吸频率的影响比较大,而在后期3 Hz频率共振影响比较大。但这2个频率的共振对大鼠体温的影响是一致的。结论持续低频共振会引起大鼠的血压、心率、呼吸频率先迅速升高后逐渐降低,还会造成大鼠体温调节能力下降。
Objective To study the changes of physiological indexes such as blood pressure, heart rate, respiratory rate and body temperature in rats under continuous low-frequency resonance, and lay the foundation for the study of resonance damage of organism and its response. Methods Thirty-two SD rats were randomly divided into sham group, 3 Hz frequency group, 6 Hz group and 21 Hz group. After anesthesia with 1.5% sodium pentobarbital, femoral artery was cannulated, The rats were then fixed in a supine position on a vibrating table. After standing for 30 min, the vibrating group was given a sinusoidal vibration with an amplitude of 5 mm (pp). Before the vibration was observed and the vibrations were 1,3,5,10,30,601,20,1802 , 40,3003,60 min blood pressure, heart rate, respiratory rate, body temperature and other physiological indicators, sham vibration group observed the physiological indicators at the corresponding time points. Results Continuous low-frequency resuscitation caused the blood pressure, heart rate and respiratory rate of rat to increase rapidly at 1 min and reach the maximum at 1 to 3 min, then gradually decrease at 3 min and then lower than normal, Will not affect the body temperature in rats, body temperature slow down after 10 min of vibration. In the initial vibration of 6 Hz frequency resonance rat blood pressure, heart rate, respiratory rate relatively large impact, and in the latter 3 Hz frequency resonance greater impact. However, the effects of resonance at these two frequencies on body temperature in rats are consistent. Conclusion Continuous low-frequency resonance can cause the rat’s blood pressure, heart rate and respiratory rate to rapidly increase first and then decrease gradually, and also cause the temperature regulating ability of rats to decrease.