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目的 :研究非小细胞肺癌 (NSCLC)患者血清可溶性细胞间粘附分子 - 1 (sICAM - 1 )水平的临床价值。方法 :收集 1 0 2例不同TNM分期的NSCLC患者血清 ,双夹心ELISA法检测sICAM - 1水平。结果 :NSCLC组血清sICAM - 1水平显著高于健康对照组 ,并与肺癌的临床分期有关。结论 :sICAM - 1对肺癌的发展、转移有重要意义 ,可作为肺癌的一项预后指标。
Objective: To investigate the clinical value of serum soluble intercellular adhesion molecule - 1 (sICAM - 1) in patients with non small cell lung cancer (NSCLC). Methods: Serum samples of 102 NSCLC patients with different TNM stages were collected. The level of sICAM - 1 was detected by double sandwich ELISA. Results: The level of sICAM - 1 in NSCLC group was significantly higher than that in healthy control group, and was related to the clinical stage of lung cancer. Conclusion: sICAM - 1 is of great significance for the development and metastasis of lung cancer and may be used as a prognostic indicator of lung cancer.