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目的：：为临床药师参与特发性膜性肾病的治疗提供参考。方法：对临床药师参与的3例特发性膜性肾病的用药情况进行分析。结果：采用糖皮质激素联合他克莫司治疗特发性膜性肾病时，需把握药物的选择、剂量、疗程、给药时间、血药浓度、不良反应等，坚持有效性和安全性的统一。结论：临床药师参与特发性膜性肾病时，需密切关注患者用药合理性、依从性和药品不良反应。“,”Objective:To provide reference for clinical pharmacists participating in the therapy of idiopathic membranous nephrop-athy patients. Methods:The drug use in 3 cases of idiopathic membranous nephropathy participated by clinical pharmacists was ana-lyzed. Results:When idiopathic membranous nephropathy was treated with glucocorticoid combined with tacrolimus, it was necessary to master the drug selection, dose and blood concentration of the drugs, course and time of the treatment and adverse reactions etc. In addition, the effectiveness and safety should be unified. Conclusion:Clinical pharmacists should pay close attention to the rational drug use, compliance of patients and adverse reactions through participating in the therapy of idiopathic membranous nephropathy.