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颅内动脉狭窄是缺血性卒中的重要原因之一。过去20年内,关于药物、血管内介入治疗颅内动脉狭窄的报道有很多,其中药物试验中WASID证实阿司匹林优于华法林,但颅内动脉狭窄度70%~99%在药物系统治疗后仍有较高的卒中风险。初期的研究提示血管成形术和支架置入术可降低此类患者的卒中风险,但缺乏前瞻、随机对照研究。因此,血管内介入术治疗症状性颅内动脉狭窄的合理性尚在研究探索中。
Intracranial stenosis is one of the important causes of ischemic stroke. Over the past 20 years, there have been many reports on drugs and endovascular interventional treatment of intracranial arterial stenosis. Among them, WASID in drug trials confirmed that aspirin is better than warfarin, but intracranial arterial stenosis ranged from 70% to 99%. After drug treatment Have a higher risk of stroke. Initial studies suggest that angioplasty and stenting may reduce the risk of stroke in these patients, but there is no prospective, randomized, controlled study. Therefore, the feasibility of endovascular interventional treatment of symptomatic intracranial artery stenosis is still under investigation.