目的 观察曲美他嗪治疗不稳定型心绞痛的疗效。方法 选择2001-03～06北京天坛医院不稳定型心绞痛病人44例,在常规治疗基础上随机分为两组,一组加用曲美他嗪,另一组应用硝酸脂类药物作为对照,服药2周。结果 治疗后两组病人每天心绞痛发作次数、硝酸甘油片消耗量比较差异无显著性(P>0.05),且两组分别较治疗前明显减少,ECG改善两组间比较差异无显著性。结论 曲美他嗪治疗不稳定型心绞痛疗效肯定,并与硝酸脂类药相似。 Objective To observe the efficacy of trimetazidine in the treatment of unstable angina pectoris. Methods Totally 44 patients with unstable angina pectoris in Beijing Tiantan Hospital from March 2001 to June 2006 were randomly divided into two groups according to the routine treatment. One group was treated with trimetazidine, and the other group was treated with nitric acid lipids as control. 2 weeks. Results After treatment, the incidence of angina pectoris and the consumption of nitroglycerin tablets in the two groups were not significantly different (P> 0.05), and the two groups were significantly decreased compared with those before treatment. There was no significant difference between the two groups in ECG improvement. Conclusions Trimetazidine is effective in treating unstable angina pectoris and is similar to nitroglycerin.