患者女性,59岁。发现左乳房肿块8年,迅速增大伴乳房胀痛1个月。专科检查:左乳头内侧可扪及直径10 cm大小的圆球形肿物,边界欠清,质硬韧,较固定;表面皮肤红肿、溃烂。双侧乳头无凹陷,无乳头溢液,乳房皮肤无水肿及橘皮征,左腋窝触及多枚肿大淋巴结。实验室检查:轻度贫血。乳腺超声示左乳腺体内有10 cm×7.8 cm大小包块,边界欠清,部分见包膜回声,内回声不均,呈斑片状强回声及 Patient female, 59 years old. Found that the left breast lumps 8 years, rapidly increased with breast pain for 1 month. Specialist examination: the left side of the papillary medial palpable diameter of 10 cm in size spherical tumor, the border is less clear, hard and tough, more fixed; surface skin irritation, ulceration. No bilateral nipple depression, nipple discharge, no breast skin edema and orange peel signs, left axillary touch multiple enlarged lymph nodes. Laboratory tests: mild anemia. Breast ultrasound showed left breast with 10 cm × 7.8 cm size of the mass, the border is not clear, part of the envelope echo, the uneven echo, was a patchy hyperechoic and