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作者应用普瑞博思治疗早产、低体重儿胃食管反流(GER),取得了满意的效果,现将临床观察报告如下。1 资料与方法1.1 病例选择全部观察对象皆符合:(1)早产;(2)低体重;(3)洗胃后仍有呕吐,喂养不耐受,体重增长缓慢;(4)出生时无明显窒息、抢救史;(5)无消化道畸形;(6)均已成活3天以上,无 HMD 发生。3组新生儿胎龄、体重资料见表1。1.2 治疗方法全部 GER 患儿采用吗丁啉悬液治疗,0.3ml/kg·次,1日3次,q8h,喂奶前半小时左右给入。采用普瑞博思治疗,0.2ml/kg·次,1日3次 q8h,喂奶前半小时左右给入,呕吐消失后维持治疗3天～7天。并设同期对照组,采用抬高体位15°,喂奶后轻轻拍背嗳气。
The application of Pregabal treatment of preterm birth, low birth weight children gastroesophageal reflux (GER), and achieved satisfactory results, the clinical observations are reported as follows. 1 Materials and Methods 1.1 Case Selection All the observed objects are in line with: (1) premature birth; (2) low body weight; (3) after gastric lavage still vomiting, feeding intolerance, slow weight gain; (4) Asphyxiation, rescue history; (5) no gastrointestinal malformations; (6) have been living more than 3 days, no HMD occurred. 3 groups of gestational age and weight of newborns in Table 1.1.2 treatment of all GER children with morphine suspension treatment, 0.3ml / kg, 3 times a day, q8h, feeding about half an hour before feeding. Pregabal treatment, 0.2ml / kg · times, 3 times on the 1st q8h, feeding about half an hour before feeding, vomiting disappeared after treatment for 3 days to 7 days. And set the same period control group, using raised position 15 °, gently patted the back after feeding gas.