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5. Study on the Binding Effect between Cordycepin and Calf Thymus DNA by Circular Dichroism

Study on the Binding Effect between Cordycepin and Calf Thymus DNA by Circular Dichroism

来源 :中国化学快报 | 被引量 : 0次 | 上传用户：zy07021023

【摘 要】

：

Binding of cordycepin to the double helical DNA with a high affinity was investigated by CD spectra in this paper. The results proved that uncoiling, unbinding

【作 者】

：

Jian Ya LING Jian Qun LIN Guo 

【机 构】

：

State Key Laboratory of Microbial Technology,Traditional Chinese Medicine of Shandong University,Sch

【出 处】

：

中国化学快报

【发表日期】

：

2004年期

【关键词】

：

Cordycepin DNA-binding CT-DNA conformation spectroscopic technique 

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Binding of cordycepin to the double helical DNA with a high affinity was investigated by CD spectra in this paper. The results proved that uncoiling, unbinding and denaturation of DNA proceeded continuously upon the increase of the concentration of cordycepin.

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