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目的:观察继发性甲状旁腺功能亢进在贫血的关系,探讨血液透析患者甲状旁腺素与血红蛋白水平的关系。方法:回顾性分析2010年3月至2012年12月广州医科大学第一附属医院收治的59例血液透析患者的资料,收取血液标本,检测血尿素氮(3un)、肌酐、血红蛋白(Hb)、铁蛋白、全段甲状旁腺素(iPTH)。结果:Bun、肌酐、Hb、铁蛋白、iPTH分别为(26.3+5.5)mol/L、(834.2±125.4)μmo1/L、(73.1±23.1)g/L、(665.3±552.2)ng/mL、(548.8±452.5)pg/m L;iPTH对Hb有显著性影响(x~2=27.142,P<0.001)。iPTH与Hb为负相关关系(r=0.565);iPTH与铁蛋白呈正相关关系(r=0.070)。结论:血透患者贫血的发生与甲状旁腺功能亢进有关,有效控制SPHT有助贫血的治疗。
Objective: To observe the relationship between secondary hyperparathyroidism and anemia and to explore the relationship between parathyroid hormone and hemoglobin in hemodialysis patients. Methods: The data of 59 cases of hemodialysis patients admitted to the First Affiliated Hospital of Guangzhou Medical University from March 2010 to December 2012 were retrospectively analyzed. The blood samples were collected for blood urea nitrogen (3un), creatinine, hemoglobin (Hb) Ferritin, whole parathyroid hormone (iPTH). Results: The levels of BUN, creatinine, Hb, ferritin and iPTH were (26.3 ± 5.5) mol / L and (834.2 ± 125.4) μmol / (548.8 ± 452.5) pg / m L; iPTH had a significant effect on Hb (x ~ 2 = 27.142, P <0.001). There was a negative correlation between iPTH and Hb (r = 0.565). There was a positive correlation between iPTH and ferritin (r = 0.070). Conclusion: The occurrence of anemia in hemodialysis patients is associated with hyperparathyroidism, and the effective control of SPHT is helpful for the treatment of anemia.