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2001年WHO关于淋巴瘤分类中,将T细胞和NK细胞肿瘤分为前体和成熟(外周)两大类。本文对成熟T/NH细胞肿瘤加以介绍。这类肿瘤在亚洲地区较常见,临床上最具有侵袭性,且对化疗有抗性,但间变性大细胞淋巴瘤对化疗反应好。作者对鼻型结外NK/T细胞淋巴瘤、肠病型T细胞淋巴瘤、母细胞性NH细胞淋巴瘤等十三型的成熟T细胞和NH细胞肿瘤的定义、病理变化、临床特点、免疫表型和遗传学分析等均分别作了叙述。
In the 2001 WHO classification of lymphoma, T-cell and NK-cell tumors were divided into two categories, precursors and mature (peripheral) tumors. This article describes mature T / NH cell tumors. These tumors are more common in Asia, the most aggressive clinical, and resistant to chemotherapy, but anaplastic large cell lymphoma respond well to chemotherapy. The author of nasal type extranodal NK / T cell lymphoma, enteric-type T-cell lymphoma, blast type NH cell lymphoma and other thirteen type of mature T cell and NH cell tumor definition, pathological changes, clinical features, immunity Phenotypic and genetic analysis were described separately.