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目的探讨纤维支气管镜下气囊导管介入治疗在复治菌阳空洞性肺结核患者中的应用效果。方法选择2015年1月至2016年6月100例复治菌阳空洞性肺结核患者作为研究对象,采用随机数表法将其分为观察组(50例)与对照组(50例)。对照组强化期2个月使用氨基水杨酸异烟肼、利福喷汀、吡嗪酰胺、丁胺卡那霉素、盐酸乙胺丁醇、左旋氧氟沙星治疗,观察组采用纤维支气管镜下气囊导管介入治疗。比较两组转阴率、病灶改善情况及不良反应。结果观察组治疗1、2个月末的痰菌转阴率均明显高于对照组,差异有统计学意义(P<0.05);治疗后,观察组空洞病灶有效率为94.00%(47/50),明显高于对照组的72.00%(36/50),差异有统计学意义(P<0.05)。结论复治菌阳空洞性肺结核患者采用纤维支气管镜下气囊导管介入治疗效果显著,能有效净化空洞、促进痰菌转阴,且无明显不良反应,可作为一种安全高效的介入疗法广泛用于临床的治疗中。
Objective To investigate the effect of balloon catheterization under bronchofibroscopy in the treatment of pulmonary v Methods 100 patients with convalescent bacilli positive pulmonary tuberculosis from January 2015 to June 2016 were selected as the research object. The patients were divided into observation group (50 cases) and control group (50 cases) by random number table method. Control group 2 months of intensive use of aminosalicylate isoniazid, rifapentine, pyrazinamide, amikacin, ethambutol hydrochloride, levofloxacin treatment, the observation group using fiber bronchus Microscopic balloon catheter interventional therapy. The rate of negative conversion, lesion improvement and adverse reaction were compared between the two groups. Results The rate of sputum negative conversion in the observation group at the end of 1 and 2 months was significantly higher than that in the control group (P <0.05). After treatment, the effective rate of the empty cavity in the observation group was 94.00% (47/50) , Significantly higher than that of the control group (72.00%, 36/50), the difference was statistically significant (P <0.05). Conclusions The treatment of pneumoconiosis-pulmonary tuberculosis patients with bronchoscopic balloon catheter intervention significantly effective, can effectively purify the cavity and promote sputum negative conversion, and no significant adverse reactions, as a safe and efficient interventional therapy is widely used in Clinical treatment.