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离体的家兔和大鼠红细胞在37℃下经γ射线照射约250、1000、3000和5000rad后2及4小时,电泳泳动度(EPM)及~(32)中掺入量均未见变化。而家兔经γ射线全身照射约600rad后2及4小时,可见红细胞EPM减慢,~(32)P掺入量增高。照射后2及4小时的家兔血浆,可导致正常家兔红细胞EPM及~(32)P掺入量相似的变化。该血浆经56℃灭活处理,仍不失其活性。家兔经约600rad照射后2及4小时,血浆cAMP含量增高,24小时后恢复。
Isolated rabbit and rat erythrocytes were irradiated at 250, 1000, 3000 and 5000 rad for 2 and 4 hours at 37 ° C by γ-rays, and the electrophoretic mobility (EPM) and the incorporation of ~ (32) were not observed Variety. However, the rabbit erythrocytes EPM slowed down and the amount of (32) P incorporation increased after 2 weeks and 4 hours irradiation with whole body irradiation of γ-rays of about 600 rads. Rabbit plasma at 2 and 4 hours after irradiation resulted in similar changes in the incorporation of EPM and ~ (32) P in normal rabbit erythrocytes. The plasma was inactivated at 56 ° C without loss of activity. Rabbits after about 600rad 2 and 4 hours after irradiation, plasma cAMP levels increased after 24 hours recovery.