目的评价rtPA静脉溶栓治疗急性心肌梗死的疗效。方法对78例STEMI病人静脉滴注rtPA进行溶栓治疗。比较距发病时间2 h、2～4 h、4～6 h、6 h以上急性心肌梗死再通率。结果分别为85.7%、80.9%、64.3%、26.7%,总再通率为65.4%。各时间段之间再通率差异均有显著性(P<0.05)。结论急性心肌梗死rtPA静脉溶栓时间越早,血管再通率越高。 Objective To evaluate the efficacy of rtPA intravenous thrombolysis in the treatment of acute myocardial infarction. Methods Thirty-eight STEMI patients received intravenous infusion of rtPA for thrombolytic therapy. The recanalization rates of acute myocardial infarction from 2 h, 2 ~ 4 h, 4 ~ 6 h and 6 h after onset were compared. The results were 85.7%, 80.9%, 64.3%, 26.7%, respectively, with a total recanalization rate of 65.4%. The recanalization rate difference between each time period was significant (P <0.05). Conclusion The earlier the rtPA intravenous thrombolysis in acute myocardial infarction, the higher the rate of recanalization.