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班氏丝虫病主要的临床症状已有大量的描述,但它与感染过程的关系仍不甚了解。本文以假设其病理过程系从一阶段到另一阶段依次地发展为依据,通过数学模型探索分析从未感染的健康人发展到无症状的微丝蚴血症,而后成为无微丝蚴血症的淋巴丝虫病的动态发展过程。数学模型按Vanamai等(1989)用的可逆催化模型。现场资料从两个地方获得,一为印度南方的本地治里,该地原为稳定的地方性流行区,从定群研究中获得感染和临床的数据。另一在加尔各答郊区,用相同方法从一项横断面研究中获得评价感染和临床表现的数据。因班氏丝虫病明显与
The main clinical manifestations of Bancroftian filariasis have been described in great detail, but its relationship to the infection process remains poorly understood. In this paper, we assume that the pathological process from one stage to another stage in turn based on the development of mathematical models to explore the development from uninfected healthy people to asymptomatic microfilaremia, and then become microfilariaemia The dynamic development of lymphatic filariasis. The mathematical model is based on the reversible catalytic model used by Vanamai et al. (1989). Field data were obtained from two locations, Pondicherry in southern India, which was originally a stable endemic endemic area, from which infection and clinical data were obtained from population-based studies. In the other suburb of Calcutta, the same method was used to obtain data from a cross-sectional study to evaluate infection and clinical manifestations. Forban filariasis obvious and