论文部分内容阅读
目的探讨炎琥宁注射液联合头孢呋辛钠治疗儿童社区获得性肺炎的临床疗效及安全性。方法选取儿童社区获得性肺炎患儿72例,随机分为治疗组和对照组,每组为36例,两组均给予头孢呋辛钠60～80 mg/kg静脉滴注,1次/d,在此基础上,治疗组加用炎琥宁注射液5～7 mg/kg静滴,1次/d;对照组加用利巴韦林10～15 mg/kg静滴,1次/d。疗程5～7 d,治疗结束后,随访3～7 d。观察比较两组体温、咳嗽、肺部啰音消失时间及治疗均平天数。结果治疗组治愈26例,有效8例,总有效率是94.44%(34/36);对照治愈22例,有效6例,总有效率77.78%(28/36)。治疗组临床总有效率高于对照组,差异有统计学意义(P<0.05)。治疗期间两组均无严重不良反应。结论炎琥宁联合头孢呋辛钠治疗儿童社区获得性肺炎,具有较好的临床疗效,安全,值得临床使用。
Objective To investigate the clinical efficacy and safety of Yanhuning injection combined with cefuroxime sodium in the treatment of community-acquired pneumonia in children. Methods Seventy-two children with community-acquired pneumonia were randomly divided into treatment group and control group, with 36 cases in each group. Cefuroxime sodium 60-80 mg / kg was given intravenously once a day, On this basis, the treatment group with Yanhuoning injection 5 ~ 7 mg / kg intravenous infusion, 1 / d; control group plus ribavirin 10 ~ 15 mg / kg intravenous infusion, 1 time / d. Course of treatment 5 ~ 7 d, after treatment, followed up for 3 ~ 7 d. Observe and compare two groups of body temperature, cough, pulmonary rales disappear time and treatment were average days. Results In the treatment group, 26 cases were cured and 8 cases were effective. The total effective rate was 94.44% (34/36). In the control group, 22 cases were cured and 6 cases were effective. The total effective rate was 77.78% (28/36). The total effective rate of the treatment group was higher than that of the control group, the difference was statistically significant (P <0.05). There was no serious adverse reaction in both groups during treatment. Conclusion Yan Hu Ning combined with cefuroxime sodium in children with community-acquired pneumonia, has good clinical efficacy, safety, worthy of clinical use.