Quantitative structure-activity relationship of compounds binding to estrogen receptor β based on h

来源 :中国科学：化学英文版 | 被引量 : 0次 | 上传用户：yudalong880210

【摘要】

：

雌激素混合物可以形成严肃的威胁到人和野生动物的健康。雌激素受体(嗯) 作为二种子类型存在，嗯并且嗯。混合物可能有不同相对亲密关系和有约束力的模式为嗯并且嗯。在这研究，

【作者】

：

ZHANG YiMing YANG XuShu SUN Ch

【机构】

：

SchoolofBasicMedicalSciences,SchoolofPharmacy,StateKeyLaboratoryofPollutionControlandResourcesReuse,

【出处】

：

中国科学：化学英文版

【发表日期】

：

2011年1期

【关键词】

：

雌激素受体启发式方法受体结合化合物定量构效关系多元线性回归野生动物预测能力 estrogen receptor β（ERβ） quantitat

【基金项目】

：

This work was supported by the Science and Technology Development Foundation Key Project of Nanjing Medical University （09NJMUZ16）.

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雌激素混合物可以形成严肃的威胁到人和野生动物的健康。雌激素受体(嗯) 作为二种子类型存在，嗯并且嗯。混合物可能有不同相对亲密关系和有约束力的模式为嗯并且嗯。在这研究，启发式的方法在对有约束力的 31 混合物上被执行嗯变化，它是然后采用了从 1524 与这项活动( LogRBA )有关最选择 5 个变化与重要关联和最好的预兆的电源开发最好的模型( r 2 = 0.829 ， q LOO2 = 0.742 ， r pred2 = 0.772 ， q ext2 = 0.724 ， RMSEE = 0.3

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Quantitative structure-activity relationship of compounds binding to estrogen receptor β based on h

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