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目的 :观察精索静脉曲张不育病人手术前后血浆生殖激素LH、FSH、E2 、PRL、T的变化情况。 方法 :运用时间分辨免疫荧光法对 3 2例精索静脉曲张不育病人手术前后血浆生殖激素进行检测。 3 2例病人中 2 8例( 87.5 0 % )为Ⅱ度 (中度 )精索静脉曲张 ,4例 ( 12 .5 0 % )为Ⅲ度 (重度 )精索静脉曲张。 结果 :治疗前 ,生殖激素异常者 18例 ,手术后生殖激素异常的病人有 11例转至正常范围。但原来生殖激素正常的 14例病人中有 2例出现异常。经统计学检验 ,全部病人手术前后生殖激素总体水平并无显著性差异。 结论 :精索静脉曲张不育病人的生殖激素多数有异常。治疗前后总体生殖激素水平无显著性差异 (P >0 .0 5 )。
Objective: To observe the changes of plasma reproductive hormones LH, FSH, E2, PRL and T before and after varicocele infertility. Methods: Time-resolved immunofluorescence was used to detect plasma reproductive hormones in 32 patients with varicocele before and after surgery. Among the 32 patients, 28 (87.5%) had grade Ⅱ (moderate) varicocele and 4 (12.5%) had grade Ⅲ (severe) varicocele. Results: Before treatment, 18 cases of abnormal reproductive hormones, reproductive hormone abnormalities in patients after surgery, 11 cases transferred to the normal range. However, two of 14 patients with normal reproductive hormones were abnormal. The statistical test showed that there was no significant difference in the overall levels of reproductive hormones between before and after surgery in all patients. CONCLUSIONS: Most reproductive hormones in patients with varicocele are abnormal. Before and after treatment, there was no significant difference in the overall level of reproductive hormone (P> 0.05).