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本文报告竹节参(罗汉三七)及大叶三七对大鼠实验性“关节炎”的治疗或抑制作用.口服三七水煎剂10克/公斤对注射鸡蛋白、甲醛、右旋糖酐所引起的大鼠实验性“关节炎”及棉球肉芽肿均有明显的抑制作用,对去肾上腺动物的甲醛性关节炎三七水煎剂仍有治疗作用.无论一次或多次口服三七水煎剂均不能使大鼠肾上腺内维生素C含量降低,也不增加肾上腺重量,表明三七水煎剂不能兴奋垂体——肾上腺系统.三七能增加正常饥饿小鼠和去肾上腺饥饿小鼠的肝糖原含量;大鼠连续服用三七后,对非特异性刺激有抑制作用;亦能延长去肾上腺未成年大鼠的生存时间。实验结果表明,三七水煎剂似具有糖皮质激素样作用,其抗炎作用可能与此有关.
This article reports on the treatment or inhibition of the experimental “arthritis” in rats by Coptis chinensis (Rhizoma Panax notoginseng) and Panax notoginseng.It is caused by the injection of 10g / kg of Panax notoginseng decoction on the injection of egg white, formaldehyde and dextran Of rat experimental “arthritis” and granuloma of cotton balls have significant inhibitory effect on the adrenal animal for arthritis of Panax notoginseng decoction still have therapeutic effect.Either one or more times of oral administration of notoginseng Agents can not make the adrenal vitamin C content decreased, nor increase the weight of the adrenal gland, that notoginseng decoction can not be excited pituitary - adrenal system.Nurstis can increase the normal starved mice and adrenal starved mice liver glycogen The content of the original rat; After taking Panax notoginseng continuously, it can inhibit the nonspecific stimulation; also prolong the survival time of adolescent adrenal rats. The experimental results show that the Panax lotus decoction may have glucocorticoid-like effect, the anti-inflammatory effect may be related to this.