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通脉灵(以下简称605)治疗硬皮病、血栓闭塞性血管炎、冠心病等疾病均获得较好的疗效,这些疾病均有缺血和缺氧,为了探讨其异病同治的基础,我们设想605可能改善局部缺血、缺氧状态,特别是改善氧的供需失调。实验材料药物:605注射液为我所药物室提取的水提酒沉制剂,1毫升含生药1克。动物:采用昆明种小鼠,体重18～22克。方法和结果 (一)减压缺氧实验;药物组腹腔注射25克/公斤体重605,对照组注入等量生理盐水,两组同时放入真空干燥器内,抽取空
Tongmailing (hereinafter referred to as 605) has a good effect in the treatment of scleroderma, thromboangiitis obliterans, coronary heart disease and other diseases, these diseases have ischemia and hypoxia, in order to explore the basis of the same disease, we It is envisaged that 605 may improve ischemic and hypoxic conditions, and in particular, improve oxygen supply and demand disorders. Experimental Materials Drugs: 605 injections were water extraction and sedimentation preparations extracted from our drug room, and 1 ml contained crude drug 1 g. Animals: Kunming mice were used, weighing 18-22 grams. Methods and results (1) Decompression and hypoxia test; the drug group was injected intraperitoneally with 25 g/kg body weight 605; the control group was injected with the same amount of physiological saline, and the two groups were placed in the vacuum drier at the same time, and the empty space was collected.