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本文应用 Nd:YAG 激光后囊切开术的64只眼,术前随机对其中的32只眼给予5mg/ml(0.5%)噻吗心安滴眼,另外32只眼不用任何药物作为对照.结果表明,激光治疗后4小时内,术前用药组的平均眼压升高显著地低于对照组(P<0.01),并于术后第2小时降压效果最明显.此外,术后24小时和48小时用药组的眼压升高仍低于对照组,但两者的差别无显著性(P>0.05).作者认为 Nd:YAG 激光后囊切开术前预先用噻吗心安滴眼,可减轻术后的急性眼压升高。虽不能完全预防后期的眼压升高,亦可减轻其眼压升高的程度。因此,噻吗心安可作为 Nd:YAG 激光后囊切开术前的常规用药,以减轻术后高眼压的不良反应.
In this study, 64 eyes of Nd: YAG laser posterior capsulotomy were treated with 5 mg / ml (0.5%) of timolol and 32 of 32 eyes without any drug as control. The results showed that the average intraocular pressure (IOP) of the preoperative medication group was significantly lower than that of the control group (P <0.01) within 4 hours after laser treatment, and the most obvious effect was achieved at the 2nd hour after the operation.At 24 hours after the operation (P> 0.05) .It is suggested that timolol can be pretreated with Nd: YAG laser posterior capsulotomy, and the intraocular pressure Can reduce postoperative acute intraocular pressure. Although it can not completely prevent the later intraocular pressure, but also reduce the degree of intraocular pressure. Therefore, timolol can be used as Nd: YAG laser posterior capsulotomy routine medication to reduce the postoperative ocular hypertension adverse reactions.