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探讨尿E/C比值与胎儿预后的关系及分娩方式对低E/C比值胎儿预后的影响,并对其临床意义进行客观评价。结果显示:在正常妊娠中有20.30%~24.43%尿E/C比值为低值,在高危妊娠中,重度妊高征和过期妊娠低E/C比值率最高,分别为44.95%和32.51%;尿E/C比值低者胎儿窘迫、低Apgar评分和围产儿死亡率明显增高(P<0.01),连续测定表明E/C比值下降者低Apgar评分和围产儿死亡率明显高于上升型和水平型(P<0.01),在尿E/C比值低值、羊水≤2cm和NST阳性的孕妇中,低Apgar评分和围产儿死亡率较高,分别为63.42%和14.63%;当低E/C比值时,产程延长和急诊剖宫产者胎儿预后不良的发生率明显增高(P<0.01)。检测孕妇尿E/C比值对监护高危妊娠、筛选胎盘功能不全、预测胎儿预后方面具有重要的临床意义。连续测定或多指标联合测定,可提高判定胎儿预后的准确性。
To investigate the relationship between urinary E / C ratio and fetal prognosis and the effect of mode of delivery on the prognosis of fetus with low E / C ratio, and evaluate its clinical significance objectively. The results showed that in normal pregnancy, there was a low E / C ratio of 20.30% to 24.43%. In high-risk pregnancies, the low E / C ratio of severe PIH and late pregnancy was the highest (44%, respectively). 95%, and 32.51%, respectively. The low urinary E / C ratio in fetal distress, low Apgar score and perinatal mortality were significantly higher (P <0.01). The continuous determination of low Apgar score and circumference The neonatal mortality rate was significantly higher than that of the ascending and the horizontal type (P <0.01). In low urinary E / C ratio, amniotic fluid ≤2cm and NST positive pregnant women, the low Apgar score and perinatal mortality were higher Were 63.42% and 14.63%, respectively. When the ratio of E / C was low, the incidence of prolonged labor and fetal malformation in emergency cesarean section was significantly higher (P <0.01). Detection of urinary E / C ratio of pregnant women monitoring of high-risk pregnancy, screening placental insufficiency, prognosis of fetal prognosis has important clinical significance. Continuous measurement or multiple indicators combined determination can improve the accuracy of the determination of fetal prognosis.