目的冠心病和患者血浆中的同型半胱氨酸、纤维蛋白的种类以及含量间的关系。方法对于拟诊为冠心病的276例患者进行了冠状动脉造影检查,发现患者中有稳定性的心绞痛的患者70例,有不稳定性心绞痛的患者66例,出现心肌梗死情况的患者64例,冠脉造影正常的患者76例。之后测量不同类型患者的血浆中的同型半胱氨酸和纤维蛋白的水平。结果冠心病各组患者的血浆中的同型半胱氨酸、纤维蛋白的水平都有所提高,但是心绞痛和冠状造影的比较无明显差异。结论冠心病患者的同型半胱氨酸、纤维蛋白水平与冠心病患者的病变程度呈正相关,上述指标水平越高,病情越重,对临床诊疗有较为重要的参考价值。 Objective The relationship between plasma levels of homocysteine ​​and fibrin types and their contents in patients with coronary heart disease. Methods 276 patients diagnosed as coronary heart disease underwent coronary angiography and found that there were 70 patients with stable angina pectoris, 66 patients with unstable angina pectoris, 64 patients with myocardial infarction, 76 patients with normal coronary angiography. The levels of homocysteine ​​and fibrin in the plasma of different types of patients were then measured. Results The levels of plasma homocysteine ​​and fibrin in patients with coronary heart disease were all improved, but there was no significant difference between angina pectoris and coronary angiography. Conclusions Homocysteine ​​and fibrin levels in patients with coronary heart disease are positively correlated with the degree of pathological changes in patients with coronary heart disease. The higher the level of these indicators, the more severe the disease, the more valuable reference value for clinical diagnosis and treatment.