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作者对450例煤工肺脏进行了尸检研究,以了解煤工肺气肿的范围与程度是否与粉尘接触量及肺内粉尘滞留量有关,这些尸检材料取自英国24个矿井,生前都有流行病学调查材料,其中342例还具有可靠的累计粉尘接触量。肺气肿的估算是根据Heard所描述的方法,即将肺大切片划分为6个区域,每个区域根据肺气肿的程度记分为0～5六个等级,故最高总分是30分。又将肺气肿分为小叶中心性(Centrtacinar)和全小叶性(Panacinar)肺气肿,前者指局限性肺气肿,后者指某个肺叶内的所有肺泡均受累。肺内粉尘是按Guest方法从干肺标本回收,提取一侧干肺的粉尘,将
The authors performed an autopsy study of 450 coal miners ’lungs to see if the extent and extent of coal workers’ emphysema were related to dust exposure and intrapulmonary dust retention. These autopsy materials were taken from 24 mines in the United Kingdom and were prevalent during their lifetime Materials for the study of the disease, of which 342 cases also have a reliable cumulative dust exposure. Emphysema is estimated according to the method described by Heard, the lung is divided into 6 large sections, each area according to the degree of emphysema score 0 to 5 six grades, so the highest total score is 30 points. The emphysema is divided into Centrtacinar and Panacinar emphysema, the former refers to the limitations of emphysema, the latter refers to all lungs within a lung are involved in all alveoli. Pulmonary dust by the Guest method is recovered from the dry lung specimens, extract the dust on the side of the dry lung, will