柳胺苄心啶(labetalol,下称Lab)是一种兼具α和β阻滞作用的药物。国外于70年代早期合成并报告其药理作用。南京大学化学系于1978年研制后,与有关单位协作进行了临床及实验观察。Lab的α和β阻滞作用强弱可因组织或机体状态不同有差异。一般认为它的α阻滞作用约为酚妥拉明的1/10 Labetalol (Labetalol, hereinafter referred to as Lab) is a both alpha and beta block drug. Abroad in the early 70s synthesis and report its pharmacological effects. Department of Chemistry, Nanjing University, developed in 1978, in collaboration with the relevant units of clinical and experimental observations. Lab α and β block the role of strength and weakness due to the organization or body state differences are different. It is generally believed that its α blockade effect is about 1/10 of phentolamine