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目的:通过研究5-羟色胺(5-HT)代谢通路相关基因5-HT1AR、SERT、MAOA、MAOB在PMS肝气郁证模型大鼠海马和下丘脑的表达,探讨该病证的发病机制及调肝方药经前舒颗粒的相关作用靶点。
OBJECTIVE: To investigate the pathogenesis and liver metastasis of rat model of PMS liver qi stagnation by studying the expression of 5-HT1AR, SERT, MAOA and MAOB related to 5-HT (5-HT) metabolic pathway in rat hippocampus and hypothalamus Prescriptions of Qianshu granules related targets.