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高剂量的化疗结合骨髓和外周血造血干细胞移植治疗多发性骨髓瘤等恶性肿瘤已获得初步成功，但肿瘤复发仍然是移植后失败的主要原因，含有微小残存癌的造血干细胞提出物的回输可能是自体造血干细胞移植失败的原因之一。本文综述了造血干细胞提出物中微小残存癌的检测及其对病人预后的意义。
High-dose chemotherapy combined with bone marrow and peripheral blood hematopoietic stem cell transplantation for the treatment of multiple myeloma and other malignancies have achieved initial success, but the tumor recurrence is still the main reason for the failure of transplantation, the remnants of the remnants of hematopoietic stem cells with minimal residual cancer may be Is one of the reasons for the failure of autologous hematopoietic stem cell transplantation. This review summarizes the detection of minimal residual cancers in hematopoietic stem cell preparations and their implications for patient prognosis.