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目的探讨布拉氏酵母菌预防婴幼儿抗生素相关性腹泻的临床疗效。方法 80例患儿均因疾病需使用抗生素药物进行治疗,随机分为对照组和研究组,每组40例,对照组在治疗过程中未给予布拉氏酵母菌预防抗生素相关性腹泻;研究组在治疗过程中使用布拉氏酵母菌预防抗生素相关性腹泻。记录两组患儿治疗期间抗生素相关性腹泻发生情况,给予统计学分析后得出结论。结果研究组抗生素相关性腹泻发生率仅为10.00%,显著低于对照组抗生素相关性腹泻发生率32.50%,差异具有统计学意义(P<0.05)。结论布拉氏酵母菌可显著降低婴幼儿抗生素相关性腹泻发生率,提高患儿预后及生活质量。
Objective To investigate the clinical efficacy of B. Cerevisiae in the prevention of antibiotic-associated diarrhea in infants. Methods 80 cases of children were treated with antibiotics due to illness, were randomly divided into control group and study group, 40 cases in each group, the control group did not give antibiotic-associated diarrhea prevention in the course of treatment; the study group Prevention of antibiotic-associated diarrhea using Brahysis during treatment. The incidence of antibiotic-associated diarrhea was recorded during treatment in both groups, and the conclusion was obtained after statistical analysis. Results The incidence of antibiotic-associated diarrhea in the study group was only 10.00%, which was significantly lower than that in the control group (32.50%). The difference was statistically significant (P <0.05). Conclusion Brachyerella could significantly reduce the incidence of antibiotic-associated diarrhea in infants and young children and improve their prognosis and quality of life.