N-Terminal Myristoylated VP5 is Required for Penetrating Cell Membrane and Promoting Infectivity in

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Dear Editor,rnMyristoylation is a naturally occurring post-translational modification for targeting cytoplasmic proteins to intracellular membranes.Unlike enveloped animal viruses,which enter host cells by membrane fusion,nonenveloped animal viruses must disrupt the cell membrane to initiate infection.Some animal viruses and several nonenveloped viruses such as reovirus and poliovirus were shown to contain myristoylated structural proteins (Ivanovic et al.2008).
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