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目的 研究脱抗原水牛角胎移植后的免疫排斥反应和成骨效应。方法 以日本大耳白兔为动物模型,分别植入经30％H2O2、0.6mol/L HCl脱抗原脱钙,30％H2O2脱抗原不脱钙2种温和方法处理的水牛角胎至兔左侧肢骨缺损处。体外检测外周血特异性T淋巴细胞转化率和ELISA检测血清特异性抗角胎IgG抗体。结果 脱抗原脱钙处理显著地降低了角胎的抗原性,与对照相比,未见受体对移植物产生显著的特异性细胞和体液免疫反应（P>0.05）,尤其是脱抗原不脱钙角胎效果更佳。两者成骨效果均良好。结论 脱抗原角胎是一种免疫原性低、成骨效果好、来源方便的骨移植材料。
Objective To study the immunological rejection and osteogenic effects of offspring Buffalo Horn Transplants. Methods The Japanese white rabbits were used as animal models and implanted with buffalo horn by 30% H2O2, 0.6 mol / L HCl decalcification, and 30% H2O2 decalin without decalcification Limb defects. Peripheral blood specific T lymphocyte transformation rate was measured in vitro and serum specific anti-angiotomy IgG antibody was detected by ELISA. Results Anti-antigen decalcification significantly reduced the antigenicity of the horn carp. No significant specific cellular and humoral immune responses were observed in the grafts compared with the control (P> 0.05), especially when the antigen was not detached Carassius better effect. Both osteogenic effect are good. Conclusion Anti-protuberance angle is a kind of bone graft material with low immunogenicity, good osteogenic effect and convenient source.