论文部分内容阅读
目的研究无创通气在中晚期妊娠重度哮喘治疗中对胎儿、动脉血气指标(pH、PaO2、PaCO2、SaO2)、心率(HR)和呼吸频率(RR)的影响。方法将30例中晚期妊娠重度支气管哮喘患者随机分为无创通气(双水平鼻/面罩NIPPV)+药物治疗组(实验组15例)和对照组(15例)。比较治疗后两组动脉血气指标(pH、PaO2、PaCO2、SaO2)变化以及对胎儿发育的影响,观察患者临床症状、HR和RR。结果实验组血气指标的改善以及监测HR、RR下降均优于对照组(P<0.01)。结论在常规药物治疗的基础上,采用双水平鼻/面罩NIPPV用于妊娠期重度哮喘的治疗,安全有效,可减少气管插管率,减少对胎儿的不良影响。
Objective To investigate the effects of noninvasive ventilation on fetal arterial blood gas (pH, PaO2, PaCO2, SaO2), heart rate (HR) and respiratory rate (RR) in the treatment of severe asthma in advanced pregnancy. Methods Thirty patients with severe gestational bronchial asthma were randomly divided into noninvasive ventilation (double horizontal nasal mask / mask NIPPV) + drug treatment group (experimental group 15 cases) and control group (15 cases). The changes of arterial blood gas index (pH, PaO2, PaCO2, SaO2) and fetal development were compared between the two groups after treatment to observe the clinical symptoms, HR and RR. Results The improvement of blood gas indexes and the decrease of HR and RR in the experimental group were better than those in the control group (P <0.01). Conclusion Based on conventional drug therapy, the double-level nasal / facial mask NIPPV is safe and effective for the treatment of severe gestational asthma. It can reduce tracheal intubation rate and reduce adverse effects on the fetus.