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目的探讨结直肠癌肝转移手术时机的选择及预后分析。方法 2000年1月至2006年1月收治的结直肠癌肝转移患者120例分为同期进行肝肿瘤切除组84例,再次手术切除肝内病灶组36例,观察两组近期、远期效果。结果同期肝肿瘤切除组、再次手术切除肝内病灶组术中出血量、输血量、住院时间、住院费用比较差异有统计学意义(P<0.05)。两组并发症发生率、病死率比较差异无统计学意义(P>0.05);两组远期1、3、5年生存率比较差异无统计学意义(P>0.05)。结论结直肠癌同期肝转移患者术前进行详细、周密的检查,掌握患者基本情况,原发结直肠癌、肝转移瘤状态及与周围关系,制定周密的手术计划,同时进行原发灶、转移灶是安全可靠的,避免了延期手术中部分患者由于肿瘤进展失去了切除转移灶的时机。
Objective To investigate the timing and prognosis of liver metastases in colorectal cancer. Methods From January 2000 to January 2006, 120 cases of colorectal cancer with liver metastasis were divided into 84 cases resected in the same period of liver tumor resection and 36 cases resected intrahepatic lesion again. The short-term and long-term effects were observed. Results There were significant differences in the amount of bleeding, blood transfusion, length of hospital stay and cost of hospitalization between the liver resection group and the resected intrahepatic lesion group during the same period (P <0.05). There was no significant difference in the incidence of complication and mortality between the two groups (P> 0.05). There was no significant difference in the 1,3 and 5-year survival rates between the two groups (P> 0.05). Conclusion Colorectal cancer patients with liver metastases over the same period before a detailed and thorough examination to grasp the basic situation of patients, primary colorectal cancer, liver metastases and their relationship with the surrounding well-developed surgical plans, while the primary tumor metastasis The stove is safe and reliable, and it avoids the opportunity that some patients in the deferred surgery lose the resection metastasis due to tumor progression.