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目的:探讨儿童颅内生殖细胞瘤的综合治疗策略。方法:回顾性分析四川省肿瘤医院收治的行综合治疗的4例儿童颅内生殖细胞瘤患者的诊疗结果,结合文献复习,制色综合治疗策略。结果:中位随访19个月。4例患者均存活,无1例出现复发和转移。智力正常,生长发育可。结论:诱导化疗联合全脑室中低剂量放疗是局限性儿童颅内生殖细胞瘤治疗的发展趋势,而脊髓放疗的指征和剂量还有待进一步的研究。
Objective: To explore the comprehensive treatment strategy for children with intracranial germinoma. Methods: The results of diagnosis and treatment of 4 cases of intracranial germinoma in children admitted to Sichuan Tumor Hospital were retrospectively analyzed. Combined with literature review and color comprehensive treatment strategy. Results: The median follow-up of 19 months. All 4 patients survived, and none developed recurrence and metastasis. Normal intelligence, growth and development can be. Conclusion: Induction chemotherapy combined with low-dose whole-brain radiotherapy is a trend of treatment of children with localized intracranial germinoma, and indications and doses of spinal radiotherapy remains to be further studied.