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目的:探讨血浆置换法治疗重型格林-巴利综合征的效果.方法:选取我院2010/2013收治的125例重型格林-巴利综合征患者进行分析,并对其进行血浆置换法治疗,设为观察组,以同期进行静脉滴注大剂量免疫球蛋白治疗的100例患者为对照组,对比两组的治疗效果及免疫球蛋白血量、血浆补体等情况.结果:观察组患者的临床效果明显优于对照组,组间比较差异具有统计学意义(P<0.05),治疗后观察组患者的血浆补体、免疫球蛋白含量均有明显降低现象,并明显优于对照组,组间比较差异具有统计学意义(P<0.05).结论:对患者进行血浆置换法,能有效改善患者的预后情况,具有科学性,值得在临床上推广应用.
Objective: To investigate the effect of plasma exchange in the treatment of severe Guillain-Barre syndrome.Methods: One hundred and twenty-five patients with severe Guillain-Barre syndrome admitted in our hospital 2010/2013 were analyzed and treated with plasma exchange. For the observation group, 100 patients treated with intravenous infusion of high-dose immunoglobulin in the same period as the control group, and compared the therapeutic effect and immunoglobulin blood volume, plasma complement, etc. Results: The clinical effect of the observation group patients (P <0.05). After treatment, the levels of plasma complement and immunoglobulin in the observation group were significantly lower than those in the control group, and were significantly better than the control group, the difference was statistically significant (P <0.05) .Conclusion: The plasma exchange method can effectively improve the prognosis of patients, which is scientific and worth popularizing in clinic.