全世界约 1 5 %的夫妇被不育所困扰 ,其中约一半为男性不育。引起男性不育的原因可以按病变所在部位的不同分为睾丸前、睾丸和睾丸后三个部位 [1]。据文献报道 ,约 40 %以上的不育男子有精子生成异常 ,但却常找不到其特殊的病原。最近几年分子生物学技术的发展和应用 ,尤其是对 About 15% of couples worldwide are plagued by infertility, about half of whom are male infertile. The causes of male infertility can be divided into different parts of the lesion according to testicular, testicular and testicular three parts [1]. According to the literature, about 40% of infertile men have abnormal sperm production, but often can not find their specific pathogen. In recent years, the development and application of molecular biology techniques, especially right