小儿癫痫全身性发作较为常见。我院应用丙戊酸钠与苯妥英钠随机分观察组与对照组治疗,结果缓解率无差异,而苯妥英钠的毒副作用明显。丙戊酸钠因其疗效较好,不良反应少,可作为治疗小儿癫癎全身性发作的首选药物。 1 临床资料 1．1 一般资料 2000年2月-2005年2月我院诊治的小儿癫癎全身性发作患者54例,男31例,女23例,男女之比1．35 :1。来院前平均病程3．2个月。年龄最小2．5岁,最大15 岁。脑电图检查:54例均有异常波型:棘波、棘慢波、尖慢波、 Systemic seizures in pediatric epilepsy are more common. In our hospital, sodium valproate and phenytoin were randomly divided into observation group and control group. There was no difference in response rate between two groups. The side effects of phenytoin sodium were obvious. Valproate sodium because of its better efficacy, fewer adverse reactions, can be used as the treatment of pediatric epilepsy systemic drug of choice. 1 Clinical data 1.1 General Information February 2000 - February 2005 in our hospital diagnosis and treatment of pediatric epilepsy in 54 patients with systemic seizures, 31 males and 23 females, the ratio of men and women 1.35: 1. The average duration of stay before hospital was 3.2 months. Youngest 2.5 years old, up to 15 years old. EEG examination: all 54 cases had abnormal wave patterns: spikes, spikes and slow waves, sharp and slow waves,