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目的:探讨母乳和配方奶两种喂养方案下极低出生体重儿生后胃电图的变化特点。方法:选择2018年1～12月在北京大学第三医院新生儿重症监护室住院的极低出生体重儿进行前瞻性研究，按照喂养方案分为母乳组和配方奶组，在出生时(第1天)、1周(第7天)、2周(第14天)、3周(第21天)分别进行餐前、餐后胃电图监测，分析极低出生体重儿胃电图特点，并比较两组患儿胃电图差异。结果:共纳入78例极低出生体重儿，母乳组40例，配方奶组38例，两组患儿生后2周、3周餐后胃电图平均幅值高于餐前，并且随着日龄增加平均幅值逐渐升高，差异有统计学意义(n P<0.05)；两组患儿餐后正常慢波百分比随着生后日龄增加而增加，母乳组生后1～3周餐后胃电图正常慢波百分比高于配方奶组，差异有统计学意义(n P0.05)，但餐后主频均会随着日龄的增加而增加(n P<0.05)。n 结论:生后早期肠内喂养可能会增强极低出生体重儿胃主动收缩能力，故提倡生后尽早开奶；母乳促进极低出生体重儿胃电成熟的作用优于配方奶，故提倡极低出生体重儿开奶尽量选择母乳。“,”Objective:To study the characteristics of electrogastrography (EGG) in very low birth weight infants(VLBWIs) with different feeding methods.Method:From January to December 2018, stable VLBWIs admitted to our hospital were assigned into two groups according to their feeding methods (the breastfeeding group and the formula group). EGG recordings were performed before and after meals at 1d, 7d, 14d and 21d after birth.Result:A total of 78 VLBWIs were included in the study, 40 in the breastfeeding group and 38 in the formula group. The average postprandial amplitude was higher than preprandial amplitude in both two groups since 14 d after birth and the average amplitude increased with the postnatal age (n P<0.05). The percentage of postprandial normal slow waves in breastfeeding group was higher than the formula group since 7 d after birth (n P<0.05), and the percentage of normal slow waves increased with the postnatal age in both groups (n P<0.05). The dominant frequency of EGG was relatively low in both two groups and no significant differences existed between the two groups.n Conclusion:Early postnatal enteral feeding may promote active gastric contractility in VLBWIs. Enteral feeding should be recommended as early as possible. Breastfeeding has advantages over formula milk in promoting gastric electrical maturation and breastfeeding should be considered as the first choice for VLBWIs.