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目的:探讨糖尿病视网膜病变(DR)的相关影响因素。方法:选择糖尿病(DM)230例,分别测定患者的体重指数、血压、空腹血糖和糖化血红蛋白、血压、24h尿微量清蛋白、血脂等项目,以及检眼镜观察视网膜病变。根据眼底病变程度,分为非糖尿病视网膜病变(NDR)组、单纯糖尿病视网膜病变组(NPDR)组和增殖型糖尿病视网膜病变组(PDR)。结果:230例中共确诊NDR 130例(56.5%)、NPDR 82例(35.7%)、PDR 18例(7.8%);三组在病程、空腹血糖、糖化血红蛋白、尿微量清蛋白含量、高血压病患病率等方面差异非常显著(P<0.01),而在年龄、体重指数、血脂等方面差异不显著(P>0.05)。结论:DM并发DR与DM病程、尿微量清蛋白含量、空腹血糖、糖化血红蛋白和血压水平有关,应注意加强相关监测。
Objective: To investigate the related factors of diabetic retinopathy (DR). Methods: Totally 230 diabetic patients were enrolled in the study. Body mass index (BMI), blood pressure, fasting blood glucose and glycosylated hemoglobin, blood pressure, 24h urinary albumin and lipids were measured. Retinopathy was observed with ophthalmoscope. According to the degree of fundus lesions, they were divided into non-diabetic retinopathy (NDR) group, simple diabetic retinopathy group (NPDR) group and proliferative diabetic retinopathy group (PDR). Results: 130 cases (56.5%) were diagnosed by NCD in 82 cases, 82 cases (35.7%) were NPDR and 18 cases were PDR (7.8%). The duration, fasting blood glucose, glycosylated hemoglobin, urine microalbumin, (P <0.01), but no significant difference in age, body mass index, blood lipid and other aspects (P> 0.05). Conclusions: The DM complicated with the course of DM, the content of urinary albumin, fasting blood glucose, glycosylated hemoglobin and blood pressure level should pay attention to strengthening the relevant monitoring.