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目的探讨急性下肢深静脉血栓(lowerextr emity deep venous thrombosis,LEDVT)腔内机械性血栓碎吸及溶栓介入治疗的疗效。资料与方法对136例急性LEDVT患者于DSA下顺行股、髂静脉造影后,在下腔静脉滤器保护下,首先行机械性大腔导管血栓碎吸治疗,然后留置导管腔内溶栓治疗。对136例中并发13例急性肺栓塞(pulmonary emblism,PE)患者也采取腔内机械性血栓碎吸和溶栓介入治疗。结果136例介入治疗有效率100%,患者平均住院时间为7.5天。患肢肿胀、疼痛均于介入治疗后1～2天内开始消退。出院时健、患肢膝关节上、下15cm处周径差及患肢膝关节上、下15cm处周径与入院时比较,差异均有统计学意义(P<0.01)。结论腔内机械性血栓碎吸及溶栓介入治疗严重急性LEDVT疗效显著,病程短,是安全、有效的方法。
Objective To investigate the therapeutic effect of intraluminal mechanical thrombus disruption and thrombolytic intervention in the treatment of acute lower extremity deep venous thrombosis (LEDVT). Materials and Methods 136 cases of acute LEDVT under DSA in the antegrade strands, iliac vein after angiography, under the protection of the inferior vena cava filter, the first mechanical large catheter thrombolysis treatment, and then catheter indwelling catheter thrombolytic therapy. 136 patients with concurrent pulmonary emblism (pulmonary emblism, PE) patients also took intraluminal mechanical thrombectomy and thrombolytic intervention. Results 136 cases of interventional treatment efficiency of 100%, the average hospital stay of 7.5 days. Limb swelling, pain were in 1 to 2 days after interventional treatment began to subside. At the time of discharge from the hospital, the difference in circumference at 15 cm above and below the knee joint and the circumference at the 15 cm above and below the knee joint were statistically significant (P <0.01). Conclusion Intraluminal mechanical thrombus fragmentation and thrombolytic intervention in the treatment of severe acute severe acute ambiguous LEDVT, short course of disease, is a safe and effective method.