Boiling flow instability of nitrogen in a vertical tube is experimentally investigated in the present study. The experiments reveal that pressure has a significant effect on the characteristics of the heat flux-mass flux type boiling flow instability. First, the pressure has strong effects on both the developing time and the fluctuation amplitude. Especially increasing pressure leads to decrease the fluctuating amplitude of mass flux. Then, the mass flux evolving curves under different pressures feature out a shape like a leaf. The characteristics of the heat flux-mass flux type boiling flow instability under lower pressure are very complicated, however, with increasing pressure, this type of instability is gradually suppressed.