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目的:探讨闭经患者与染色体之间的关系,为诊断及治疗提供相关依据。方法:常规妇科检查及外周血淋巴细胞培养和G显带分析。结果:89例原发性闭经患者中发现异常核型25例,异常率58.09%,均为性染色体异常,39例继发闭经患者发现7例异常,异常率17.95%,其中性染色体异常4例、染色体多态2例。结论:无论是原发性闭经患者,还是继发性闭经患者,进行染色体检查是十分必要的。
Objective: To explore the relationship between amenorrhea patients and chromosomes, to provide relevant evidence for diagnosis and treatment. Methods: routine gynecological examination and peripheral blood lymphocyte culture and G - banding analysis. Results: Of the 89 patients with primary amenorrhea, 25 cases were abnormal karyotypes, the rate of abnormality was 58.09%. All of them were sex chromosome abnormalities. Among 39 cases of secondary amenorrhea patients, 7 cases were abnormal and the abnormal rate was 17.95%. There were 4 cases of chromosomal abnormalities , Chromosome polymorphism in 2 cases. CONCLUSION: Chromosomal examination is essential for both primary amenorrhea patients and secondary amenorrhea patients.