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在上一届全国药物分析学术研讨会上(1995,上海),我们讨论了基质辅助激光解吸离子化质谱法(MALDI/MS)和液相色谱/质谱法(LC/MS)在药物分析中的初步应用,主要涉及多肽蛋白质的分析[1]。本文综合报道我们的工作,讨论电喷雾离子化质谱法(EMII/MS)及其联用技术(L
At the last National Symposium on Pharmaceutical Analysis (Shanghai, 1995), we discussed the use of matrix-assisted laser desorption ionization mass spectrometry (MALDI / MS) and liquid chromatography / mass spectrometry (LC / MS) Preliminary application, mainly related to the analysis of peptide proteins [1]. This article is a comprehensive report of our work to discuss electrospray ionization mass spectrometry (EMII / MS) and its associated technology (L