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目的探讨肺癌患者同步放射化学治疗(放化疗)期间的症状发生频率及严重程度以及相关症状群对患者日常生活的影响。方法 2016年12月—2017年6月期间采用中文版安德森癌症症状调查量表、修订版肺癌特异性症状模块对150例同步放化疗肺癌患者进行调查。结果肺癌患者同步放化疗期间症状强度较严重(>5分)的有疲乏、恶心、食欲下降、咳嗽、苦恼、睡眠不安、呕吐、咳痰、悲伤;发生频率>80%的症状分别为疲乏、恶心、睡眠不安、食欲下降、悲伤和咳嗽。症状困扰发生率较高的依次是生活乐趣(87.33%)、情绪(74.38%)、工作(72.67%)。采用探索性因子提取放化疗同步期间肺癌的症候群,包括疲乏相关症状群、消化道症状群、情绪症状群、呼吸道症状群。结论肺癌患者放化疗同步期间普遍存在症状困扰,并存在多种症状群,对患者日常生活造成较为严重的影响。医护人员应及时进行评估,给予护理干预,提高患者生活质量。
Objective To investigate the frequency and severity of symptoms during concurrent radiochemotherapy (chemoradiotherapy) in lung cancer patients and the effects of related symptoms on patients’ daily life. Methods Between December 2016 and June 2017, 150 Chinese patients with lung cancer undergoing concurrent chemoradiotherapy were investigated by using the Chinese version of Anderson’s Cancer Symptom Inventory and a revised version of the lung cancer-specific symptoms module. Results Symptoms of fatigue, nausea, decreased appetite, cough, distress, restlessness, vomiting, expectoration and sadness during the concurrent chemoradiation of lung cancer patients were more severe during symptomatic chemotherapy and radiotherapy. The symptoms of> 80% frequency were fatigue, Nausea, restless sleep, loss of appetite, sadness and coughing. Followed by the higher incidence of symptoms of pleasure of life (87.33%), emotional (74.38%), work (72.67%). Exploratory factors were used to extract lung cancer syndromes during concurrent chemoradiotherapy, including fatigue-related symptoms, gastrointestinal symptoms, emotional symptoms and respiratory symptoms. Conclusions There are common symptoms during radiotherapy and chemotherapy in patients with lung cancer and there are many symptoms, which have a more serious impact on daily life of patients. Health care workers should be assessed in time to give nursing interventions to improve the quality of life of patients.