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碲氢化钠是一个用途广泛的磁试剂,自作为有用的去溴试剂以来,日益受到化学工作者的关注,不断有文献报道它的合成及应用.例如能有效地还原卤代烃、硝基化合物、叠氮化合物和亚胺等.近年来,Katritzky报道了胺烷基化苯并三氮唑衍生物的合成及应用,此衍生物中的苯并三氮唑基是很好的离去基团,易被各种亲核试剂所取代.我们在前文中对硒氢化钠与胺烷基化苯并三氮唑反应生成二苄基二硒醚的合成进行了报道.本文用碲氢化钠与胺烷基化苯并三氮唑反应,结果生成还原产物N-取代胺.
Sodium telluride hydride is a widely used magnetic reagent, and has been attracting more and more attention from chemists since it is a useful debromination reagent, and its synthesis and application have been continuously reported in the literature, for example, it can effectively reduce halogenated hydrocarbons, nitro compounds , Azide and imine etc. In recent years, Katritzky reported the synthesis and application of amine alkylated benzotriazole derivatives, the benzotriazole radical in this derivative is a good leaving group , Easily substituted by various nucleophiles.We have reported the synthesis of dibenzyl diselenide by the reaction of sodium selenide and amine alkylated benzotriazole in the previous article.In this paper, sodium tellurium hydride and amine The alkylated benzotriazole reacts, resulting in the reduction of the N-substituted amine.