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目的:观察双黄连口服液联合盐酸雷尼替丁胶囊治疗口腔溃疡的临床疗效。方法:选择本院治疗的96例口腔溃疡患者为研究对象,随机分为联合组和对照组各48例。对照组给予盐酸雷尼替丁胶囊内粉末涂抹溃疡处和周围组织,联合组涂抹双黄连口服液和盐酸雷尼替丁胶囊内粉末治疗。2组均治疗2周,比较2组的临床疗效,观察2组患者的口腔溃疡愈合情况、周围黏膜情况、疼痛程度,以及发生口腔异味等不良反应情况。结果:临床疗效总有效率联合组为93.75%,对照组为79.17%,2组比较,差异有显著性意义(P<0.05)。2组患者治疗过程中均有口腔异味,但均轻微可耐受,无其他显著不良反应。结论:双黄连口服液联合盐酸雷尼替丁胶囊治疗口腔溃疡患者,能显著改善临床症状,不良反应少,临床疗效确切,值得推广使用。
Objective: To observe the clinical efficacy of Shuanghuanglian oral liquid combined with ranitidine hydrochloride capsule in the treatment of oral ulcer. Methods: 96 cases of oral ulcer patients treated in our hospital were selected as study subjects and randomly divided into the combined group and the control group of 48 cases. The control group was given Ranitidine Hydrochloride Capsule powder smear ulcer and surrounding tissue, the combination group smear Shuanghuanglian oral liquid and ranitidine hydrochloride capsule powder treatment. The two groups were treated for 2 weeks. The clinical curative effect of the two groups were compared. The healing status of oral ulcer, the surrounding mucosa, the degree of pain and the occurrence of bad smell in oral cavity were observed. Results: The total effective rate was 93.75% in the combined group and 79.17% in the control group. There was significant difference between the two groups (P <0.05). Oral odor was observed in both groups during the course of treatment, but both were slightly tolerable with no other significant adverse reactions. Conclusion: Shuanghuanglian oral liquid combined with ranitidine hydrochloride capsules in patients with oral ulcer can significantly improve clinical symptoms, fewer adverse reactions, the exact clinical efficacy, it is worth promoting the use of.