万可霉素(Vancomycin)是最近广用在临床上的一种新抗菌素,临床上常用的是其鹽酸鹽。外国商品名为Vancocin。因为它对革蘭氏阳性球菌有高度的作用,特别是对于对一般抗菌素有抗药性的革蘭氏阳性球菌所引起的疾病仍同样有高效,因此万可霉素的發现和应用,解决了近年来医疗上存在的一大間题,即如何克服由于广泛应用青霉素等抗菌素而产生的有抗药性的革蘭氏阳性球菌感染的治疗问題。这是抗菌素在治疗上一个重大的进展。来源和性质:万可霉素是从Streptomyces orientalis菌培养基中分离所得。结構式还沒有确定。游离的万可霉素,元素分析结果,已知其分子中含C,H,N,Cl而不含S和P。不溶于水而易溶于二甲基亚碸或二甲基乙酰胺等有机溶剂中。分子中含有羧基、氨基 Vancomycin is a new antibiotic that has been widely used in clinical practice. Its hydrochloride is commonly used clinically. Foreign trade name is Vancocin. Because it has a high degree of effect on Gram-positive cocci, especially for diseases caused by Gram-positive cocci that are resistant to general antibiotics, the discovery and application of vancomycin is also solved In recent years there is a major medical problem, that is, how to overcome the widespread use of antibiotics such as penicillin and antibiotic-resistant Gram-positive cocci infection treatment problems. This is a major advance in the treatment of antibiotics. Source and nature: Vancomycin is isolated from Streptomyces orientalis culture medium. Structure has not been determined. Free vancomycin, elemental analysis results, known molecules containing C, H, N, Cl without S and P. Do not dissolve in water and soluble in dimethyl sulfoxide or dimethylacetamide and other organic solvents. Molecular contains carboxyl, amino